How much is the breast cancer liquid biopsy market worth, and how is it expected to expand?
The breast cancer liquid biopsy market size has grown rapidly in recent years. It will grow from $0.78 billion in 2024 to $0.90 billion in 2025 at a compound annual growth rate (CAGR) of 15.0%. The growth in the historic period can be attributed to advancements in next-generation sequencing (ngs), increasing prevalence of breast cancer, growing demand for non-invasive diagnostic methods, rising adoption of personalized medicine, and increased funding for cancer research.
The breast cancer liquid biopsy market size is expected to see rapid growth in the next few years. It will grow to $1.56 billion in 2029 at a compound annual growth rate (CAGR) of 14.7%. The growth in the forecast period can be attributed to technological advancements in liquid biopsy assays, increasing adoption of liquid biopsy in early cancer screening, rising demand for real-time cancer monitoring, expanding applications in precision oncology, growing investments in liquid biopsy research and development. Major trends in the forecast period include integration of artificial intelligence in liquid biopsy analysis, advancements in single-cell sequencing, development of multi-omics liquid biopsy platforms, improvement in liquid biopsy sensitivity and specificity, and adoption of digital pcr for ultra-precise mutation detection.
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Which industry factors have accelerated the breast cancer liquid biopsy market’s expansion?
The increase in breast cancer cases is expected to propel the growth of the breast cancer liquid biopsy market going forward. Breast cancer is a type of cancer that develops in the cells of the breast, typically in the lobules (milk-producing glands) or ducts (pathways that carry milk to the nipple). Breast cancer cases are on the rise due to factors including genetic predisposition, hormonal imbalances, aging population, lifestyle changes, obesity, alcohol consumption, lack of physical activity, exposure to radiation, and environmental pollutants. A breast cancer liquid biopsy is used in treatment to detect circulating tumor DNA (ctDNA) or circulating tumor cells (CTCs) in the blood, helping to monitor the disease in real-time. It aids in assessing treatment response, detecting therapy resistance, and identifying genetic mutations for targeted therapies. For instance, in 2025, according to the American Cancer Society, a US-based nonprofit organization dedicated to cancer research, education, advocacy, and patient support, the number of new breast cancer cases is expected to rise to 319,750 in 2025, up from 313,510 cases in 2024. Therefore, the increase in breast cancer cases is driving the growth of the breast cancer liquid biopsy market.
What are the primary segments of the breast cancer liquid biopsy market?
The breast cancer liquid biopsy market covered in this report is segmented –
1) By Product: Consumables, Kits
2) By Biomarkers: Extracellular Vesicles (EVs), Cell-free DNA (cfDNA), Circulating Tumor RNA (ctRNA), Circulating Tumor Cells (CTCs), Cell-free RNA (cfRNA), Other Biomarkers
3) By Application: Early Detection Or Screening, Diagnosis, Other Applications
4) By End Users: Laboratories, Hospitals, Physician Laboratories, Reference Laboratories, Public Health Laboratories, Research Institutes, Small Molecular Laboratories, Pathology Laboratories
Subsegments:
1) By Consumables: Reagents, Polymerase Chain Reaction (PCR) Assays, Sequencing Panels, Sample Collection Tubes
2) By Kits: DNA-based Liquid Biopsy Kits, RNA-based Liquid Biopsy Kits, Multi-marker Liquid Biopsy Kits
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Which firms are leading the breast cancer liquid biopsy market?
Major companies operating in the breast cancer liquid biopsy market are Johnson & Johnson Private Limited, Roche Diagnostics, Merck KGaA, Thermo Fisher Scientific, Siemens Healthineers, Agilent Technologies Inc., Illumina Inc., Sysmex Corporation, Qiagen N.V., Myriad Genetics Inc., NeoGenomics Laboratories, Guardant Health Inc., Twist Bioscience, Foundation Medicine Inc., Biodesix Inc., Menarini Silicon Biosystems, Datar Cancer Genetics, Abcam plc, OncoDNA SA, Genomic Health Inc., RainDance Technologies, Biocept Inc., Fluxion Biosciences Inc., Angle plc
Which market trends are set to define the future of the breast cancer liquid biopsy market?
Major companies operating in the breast cancer liquid biopsy market are focusing on developing innovative products, such as companion diagnostics, to enable personalized treatment approaches by identifying patients who benefit from specific therapies. Companion diagnostics utilize liquid biopsy technologies to detect biomarkers such as genetic mutations, circulating tumor DNA (ctDNA), or protein expressions indicative of treatment responsiveness. For instance, in January 2023, Guardant Health Inc., a US-based biotechnology company, received Food and Drug Administration (FDA) approval for its Guardant360 CDx liquid biopsy test as a companion diagnostic for Menarini Group’s ORSERDU (elacestrant), a treatment for advanced or metastatic breast cancer patients with ESR1 mutations. This approval enables oncologists to use the test for comprehensive genomic profiling, identifying patients who may benefit from the targeted therapy. It marks Guardant Health’s first U.S. Food and Drug Administration (FDA) approval in breast cancer and expands its role in precision oncology.
Which geographic trends are shaping the breast cancer liquid biopsy market, and which region has the highest market share?
North America was the largest region in the breast cancer liquid biopsy market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the breast cancer liquid biopsy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Does The Breast Cancer Liquid Biopsy Market Report 2025 Offer?
The breast cancer liquid biopsy market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
A breast cancer liquid biopsy is a minimally invasive test that detects and analyzes tumor-derived materials in a patient’s blood or other bodily fluids. It provides valuable insights into the presence, progression, and genetic profile of breast cancer without requiring a traditional tissue biopsy.
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