Overview and Scope
RNA targeting small-molecule drug discovery refers to identifying and developing small-molecule drugs that interact with RNA molecules to modulate their function or activity. This process is used for discovering innovative medicines that would be used for treating various diseases, including genetic disorders, viral infections, neurodegenerative diseases, and cancer.
Sizing and Forecast
The rna targeting small molecule drug discovery market size has grown exponentially in recent years. It will grow from $1.45 billion in 2023 to $1.78 billion in 2024 at a compound annual growth rate (CAGR) of 22.3%. The growth in the historic period can be attributed to increased understanding of disease genetics, genomic and proteomic discoveries, drug resistance challenges, investment in biotechnology and pharmaceutical research, rise of rna therapeutics.
The rna targeting small molecule drug discovery market size is expected to see exponential growth in the next few years. It will grow to $3.97 billion in 2028 at a compound annual growth rate (CAGR) of 22.2%. The growth in the forecast period can be attributed to expansion of rna epigenetics research, rna-seq and functional genomics, integration of artificial intelligence (ai),patient-centric approaches, exosome-mediated drug delivery. Major trends in the forecast period include emergence of rna editing technologies, advancements in crispr technology, technological innovations, advancements in rna biology, rna targeting in neurodegenerative diseases.
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Segmentation & Regional Insights
The rna targeting small molecule drug discovery market covered in this report is segmented –
1) By Target RNA Type: Messenger RNA (mRNA), Non-Coding RNA (ncRNA), MicroRNA (miRNA), Long Non-Coding RNA (lncRNA)
2) By Technology: CRISPR-Cas9, RNA Aptamers, Small Interfering RNA (siRNA), Ribozymes, Other Technologies
3) By Therapeutic Area: Oncology, Neurology, Infectious Disease, Metabolic Diseases, Genetic Disorders, Other Therapeutic Areas
4) By Delivery Method: Intravenous (IV), Oral, Topical, Other Methods
5) By Application: Research Use, Therapeutic Use, Diagnostic Use, Other Applications
Top 5 Major Players:
- F. Hoffmann-La Roche Ltd
- Merck & Co. Inc
- Bayer AG
- Novartis AG
- Sanofi SA
North America was the largest region in the RNA targeting small molecule drug discovery market in 2023. The regions covered in the rna targeting small molecule drug discovery market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
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Major Driver Impacting Market Growth
The increasing prevalence of cancer, genetic disorders, and viral infections is expected to propel the growth of the RNA-targeted small-molecule drug discovery market going forward. Cancer is a group of diseases characterized by the uncontrollable growth of cells in the body. Viral infections refer to infections caused by viruses, tiny infectious agents that can only replicate inside the cells of living organisms. RNA targeting-based drug discovery is used to treat cancer, genetic disorders, and viral infections, as these diseases are linked with genes and malfunctioning genetic material, which can be treated using drugs developed using RNA targeting-based methods. For instance, in February 2021, according to the American Cancer Society, a US-based voluntary Health Organization, new cancer cases and cancer deaths number is expected to increase by 47% by 2040, reaching about 28.4 million cases. Furthermore, in 2021, according to the World Health Organization, a Switzerland-based specialized health agency of the United Nations, approximately 38.4 million people were living with HIV, and 650,000 people died due to HIV. Therefore, the increasing prevalence of cancer, genetic disorders, and viral infections drives the growth of the RNA-targeted small-molecule drug discovery market.
Key Industry Players
Major companies operating in the rna targeting small molecule drug discovery market report are F. Hoffmann-La Roche Ltd , Merck & Co. Inc, Bayer AG, Novartis AG, Sanofi SA, Bristol-Myers Squibb Company, AstraZeneca PLC, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Amgen Inc., Novo Nordisk Inc., Moderna Inc., Astellas Pharma Inc., Biogen Inc., Alnylam Pharmaceuticals Inc., Sarepta Therapeutics Inc., Evotec A.G., PTC Therapeutics Inc., Ionis Pharmaceuticals Inc., Dicerna Pharmaceuticals Inc., Arrakis Therapeutics, Arbutus Biopharma Corporation, H3 Biomedicine Inc., Anima Biotech Inc., Ribometrix Inc., Quark Pharmaceuticals Inc., Regulus Therapeutics Inc., Skyhawk Therapeutics Inc., Accent Therapeutics Inc., Epics Therapeutics, Expansion Therapeutics
The rna targeting small molecule drug discovery market report table of contents includes:
1. Executive Summary
2. RNA Targeting Small Molecule Drug Discovery Market Characteristics
3. RNA Targeting Small Molecule Drug Discovery Market Trends And Strategies
4. RNA Targeting Small Molecule Drug Discovery Market – Macro Economic Scenario
5. Global RNA Targeting Small Molecule Drug Discovery Market Size and Growth
….
32. Global RNA Targeting Small Molecule Drug Discovery Market Competitive Benchmarking
33. Global RNA Targeting Small Molecule Drug Discovery Market Competitive Dashboard
34. Key Mergers And Acquisitions In The RNA Targeting Small Molecule Drug Discovery Market
35. RNA Targeting Small Molecule Drug Discovery Market Future Outlook and Potential Analysis
36. Appendix
List Of Tables:
Table 1: Global Historic Market Growth, 2018-2023, $ Billion
Table 2: Global Forecast Market Growth, 2023-2028F, 2033F, $ Billion
Table 3: Global RNA Targeting Small Molecule Drug Discovery Market, Segmentation By Target RNA Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Table 4: Global RNA Targeting Small Molecule Drug Discovery Market, Segmentation By Technology, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Table 5: Global RNA Targeting Small Molecule Drug Discovery Market, Segmentation By Therapeutic Area, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
…
Table 76: F. Hoffmann-La Roche Ltd Financial Performance
Table 77: Merck & Co. Inc Financial Performance
Table 78: Bayer AG Financial Performance
Table 79: Novartis AG Financial Performance
Table 80: Sanofi SA Financial Performance
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