How big is the actinic keratosis market today, and what are its future growth expectations?
The actinic keratosis market size has grown steadily in recent years. It will grow from $7.95 billion in 2024 to $8.44 billion in 2025 at a compound annual growth rate (CAGR) of 6.1%. The growth in the historic period can be attributed to rising uv radiation exposure, aging population, increasing awareness of skin cancer, growing prevalence of actinic keratosis, expanding healthcare infrastructure, higher disposable incomes, supportive government initiatives and increasing focus on preventive skincare.
The actinic keratosis market size is expected to see exponential growth in the next few years. It will grow to $10.58 billion in 2029 at a compound annual growth rate (CAGR) of 7.4%. The growth in the forecast period can be attributed to emergence of innovative therapies, advancements in AI-powered diagnostic tools, increasing adoption of combination treatments, rising demand for non-invasive procedures, growing use of tele dermatology, expanding application of photodynamic therapy, increased awareness of cosmetic outcomes, development of targeted biologic treatments, rising healthcare investment in emerging markets and growing focus on early detection and prevention. Major trends in the forecast period include AI-driven diagnostic tools, machine learning for lesion analysis, advanced photodynamic therapy systems, wearable uv monitoring devices, nanotechnology-based drug delivery, 3d imaging for personalized treatments, portable home-based phototherapy devices, biosensors for early detection, automated lesion classification software and hydrogel-based therapeutic systems.
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What have been the primary factors driving the actinic keratosis market’s growth?
The increasing cases of severe sunburns is expected to propel the growth of the actinic keratosis market going forward. Severe sunburns are intense skin burns caused by excessive exposure to ultraviolet (UV) radiation, resulting in redness, pain, swelling, and sometimes blistering. Sunburns are attributed due to factors such as prolonged exposure to ultraviolet (UV) radiation, lack of proper sun protection measures, increased outdoor activities during peak UV hours and rising temperatures due to climate change. Sunburns cause actinic keratosis by damaging the DNA in skin cells through ultraviolet (UV) radiation, leading to mutations that disrupt normal cell function, resulting in the development of precancerous lesions, especially with repeated or prolonged sun exposure. For instance, in May 2024, according to Melanoma Focus, a UK-based charity, in 2022-23, there were 201 hospital admissions due to sunburn, including 89 children and 25 babies under one year old. The charity also found that 66% of UK adults aged 16-65 remembered getting sunburned as children, 65% of them experienced severe sunburn with blisters at least once. This number rose to 77% for those with light, pale, or white skin. Therefore, the increasing cases of severe sunburns is driving the growth of the actinic keratosis market.
What are the key segments within the actinic keratosis market?
The actinic keratosis market covered in this report is segmented –
1) By Treatment Type: Topical Treatment, Surgical Procedure, Photodynamic Therapy, Other Treatment Types
2) By Distribution Channels: Hospital Pharmacies, Drug Stores And Retail Pharmacies, Online Providers
3) By End-User: Hospitals, Dermatology Clinics, Spas And Rejuvenation Centers, Homecare Settings, Other End-Users
Subsegments:
1) By Topical Treatment: 5-Fluorouracil (5-FU), Imiquimod, Diclofenac, Ingenol Mebutate, Retinoids
2) By Surgical Procedure: Cryotherapy, Curettage And Electrodessication, Excision
3) By Photodynamic Therapy: Aminolevulinic Acid (ALA) Plus Light Therapy, Methyl Aminolevulinate (MAL) Plus Light Therapy
4) By Other Treatment Types: Laser Therapy, Chemical Peels, Combination Therapies
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Which key players are shaping the actinic keratosis market?
Major companies operating in the actinic keratosis market are Pfizer Inc., F. Hoffmann-La Roche AG, Merck & Co. Inc., AbbVie Inc., Sanofi S.A., Bristol-Myers Squibb, Novartis AG, GSK plc, Amgen Inc., Bausch Health Companies Inc., Perrigo Company plc, Galderma SA, Incyte Corporation, Leo Pharma Inc., Almirall S.A., Athenex Inc., G&E Herbal Biotechnology Co. Ltd., Aclaris Therapeutics Inc., Biofrontera Inc., Hill Dermaceuticals Inc.
How will emerging trends drive the actinic keratosis market throughout the forecast period?
Major companies operating in the actinic keratosis market are focusing on developing topical ointments to effectively target and eliminate precancerous lesions, reduce recurrence rates and enhance patient compliance with shorter treatment durations and improved safety profiles. Topical ointments are medicated creams or gels applied directly to the affected skin with active ingredient such as tirbanibulin which work by targeting abnormal keratinocytes to treat precancerous lesions. For instance, in June 2024, Almirall SA, a Spain-based biopharmaceutical company, received approval from the US Food and Drug Administration (FDA) for supplemental new drug application (sNDA) to expand the use area for its drug, Klisyri, to upto 100 cm2. Klisyri (tirbanibulin) 1% ointment is a microtubule inhibitor, designed to prevent the proliferation of abnormal keratinocytes, effectively reducing the number and size of precancerous lesions for the treatment of actinic keratosis (AK) on the face or scalp.
How do regional factors impact the actinic keratosis market, and which region is the largest contributor?
North America was the largest region in the actinic keratosis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the actinic keratosis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Does The Actinic Keratosis Market Report 2025 Offer?
The actinic keratosis market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
Actinic keratosis (AK), also known as solar keratosis, is a common precancerous skin condition that occurs due to prolonged exposure to ultraviolet (UV) radiation from the sun or artificial sources leading to rough, scaly or crusty patches on sun-exposed areas of the skin such as the face, scalp, hands and arms. It is considered an early stage of squamous cell carcinoma (SCC) and requires treatment to prevent progression. Regular skin checks and protection from sun exposure are essential for managing and preventing the development of actinic keratosis.
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