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How big is the advanced liver cancer market today, and what are its future growth expectations?
The advanced liver cancer market size has grown rapidly in recent years. It will grow from $1.89 billion in 2024 to $2.17 billion in 2025 at a compound annual growth rate (CAGR) of 15.2%. The growth in the historic period can be attributed to increasing awareness towards liver cancer, increasing patient pool, growing demand for targeted therapies, expanding healthcare infrastructure, and growing demand for minimally invasive treatments.
The advanced liver cancer market size is expected to see rapid growth in the next few years. It will grow to $3.78 billion in 2029 at a compound annual growth rate (CAGR) of 14.8%. The growth in the forecast period can be attributed to the growing incidence of liver cancer, incremental healthcare spending, increasing prevalence of genetic conditions, increasing adoption of precision medicine, and increasing adoption of screening and diagnostic tests. Major trends in the forecast period include the integration of artificial intelligence in treatment, the development of innovative drugs and treatment, expanding research and development activities, the development in targeted therapeutics, and growing demand for personalized medicine.
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What have been the primary factors driving the advanced liver cancer market’s growth?
The rising prevalence of long-term hepatitis infections is expected to propel the growth of the advanced liver cancer market going forward. Long-term hepatitis infections are long-lasting viral infections that endure for over six months and can result in liver damage, cirrhosis, or liver cancer. The increase in long-term hepatitis infections can be attributed to factors such as inadequate screening and vaccination and delayed access to treatment. Chronic infections with hepatitis B (HBV) or hepatitis C (HCV) are among the leading causes of liver cirrhosis and hepatocellular carcinoma (HCC), the most common form of liver cancer. Long-term viral infections can lead to liver inflammation, liver damage, and eventually cancer over time. As these infections remain prevalent, more individuals are at risk of developing advanced liver cancer. For instance, in April 2024, according to the World Health Organization, a Switzerland-based intergovernmental organization, in 2022, chronic hepatitis B affected 254 million people worldwide, with 1.2 million new cases reported each year. Therefore, the rising prevalence of long-term hepatitis infections is driving the growth of the advanced liver cancer market.
What are the key segments within the advanced liver cancer market?
The advanced liver cancer market covered in this report is segmented –
1) By Test Type: Imaging Test, Biopsy, Genomic Test, Other Test Types
2) By Technology: Fluorescent In Situ Hybridization, Next Generation Sequencing, Fluoroimmunoassay, Comparative Genomic Hybridization, Immunohistochemical, Other Technologies
3) By Distribution Channel: Direct Tenders, Retail Sales, Other Distribution Channel
4) By Application: Screening, Diagnostic And Predictive, Prognostic, Research
5) By End-User: Hospitals, Cancer Research Centers, Academic Institutes, Diagnostic Centers, Ambulatory Surgical Centers, Other End-Users
Subsegments:
1) By Imaging Test: Ultrasound, CT (Computed Tomography) Scan, MRI (Magnetic Resonance Imaging), PET (Positron Emission Tomography) Scan
2) By Biopsy: Needle Biopsy, Laparoscopic Biopsy, Surgical Biopsy
3) By Genomic Test: Next-Generation Sequencing (NGS), PCR (Polymerase Chain Reaction) Testing, Genetic Mutation Profiling
4) By Other Test Types: Serum Biomarker Testing, Liver Function Tests, Alpha-Fetoprotein (AFP) Test, Elastography Tests
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Which key players are shaping the advanced liver cancer market?
Major companies operating in the advanced liver cancer market are Pfizer Inc., F. Hoffmann-La Roche AG, Merck Co. Inc., Bayer AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca plc, Novartis AG, Eli Lilly and Company, Stryker Corporation, Agilent Technologies Inc., Eisai Co. Ltd., Jiangsu Hengrui Pharmaceutical Co. Ltd, Exelixis Inc., Sirtex Medical Limited, Eureka Therapeutics, Abbisko Therapeutics Co. Ltd., Binhui Biopharmaceutical Co. Ltd., Tempest Therapeutics Inc., Auransa Inc., Mina Alpha Limited, Jennerex Inc.
How will emerging trends drive the advanced liver cancer market throughout the forecast period?
Major companies operating in the advanced liver cancer market are focusing on developing innovative drugs, such as human monoclonal antibodies, to improve treatment efficacy and minimize side effects for better patient outcomes. A human monoclonal antibody is a lab-created molecule that imitates the immune system’s function in combating harmful pathogens or cancer cells. It targets specific antigens on the surface of these harmful entities to trigger an immune response. For instance, in October 2022, AstraZeneca, a US-based pharmaceutical company, announced that the US Food and Drug Administration (FDA) approved Imjudo (tremelimumab) in combination with Imfinzi (durvalumab) for the treatment of adult patients with unresectable hepatocellular carcinoma (HCC), the most common form of liver cancer. This approval was based on results from the HIMALAYA Phase III trial, which demonstrated that this combination therapy reduced the risk of death by 22% compared to sorafenib, with approximately 31% of patients alive after three years versus 20% for those on sorafenib. The regimen, known as STRIDE, involves a single dose of Imjudo followed by regular doses of Imfinzi every four weeks, offering a new therapeutic option for patients facing limited treatment choices.
How do regional factors impact the advanced liver cancer market, and which region is the largest contributor?
North America was the largest region in the advanced liver cancer market in 2024.Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the advanced liver cancer market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Does The Advanced Liver Cancer Market Report 2025 Offer?
The advanced liver cancer market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
Advanced liver cancer, also known as hepatocellular carcinoma (HCC) in its later stages, refers to liver cancer that has spread beyond the liver or grown large enough to affect liver function significantly. In this stage, the cancer may have invaded nearby blood vessels, lymph nodes, or distant organs, making treatment more challenging. Symptoms often include jaundice, abdominal pain, weight loss, and fatigue.
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