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What is the current market size and future outlook for the bioengineered skin substitutes market?
The bioengineered skin substitutes market size has grown rapidly in recent years. It will grow from $2.18 $ billion in 2024 to $2.48 $ billion in 2025 at a compound annual growth rate (CAGR) of 13.7%. The growth in the historic period can be attributed to increasing investment in R&D, improving healthcare infrastructure, increasing a number of reconstructive and cosmetic surgeries, increasing healthcare spending and improving patient outcomes.
The bioengineered skin substitutes market size is expected to see rapid growth in the next few years. It will grow to $4.11 $ billion in 2029 at a compound annual growth rate (CAGR) of 13.5%. The growth in the forecast period can be attributed to the development of new biomaterials, regulatory developments, government initiatives and funding, cost-effectiveness and long-term benefits and growing aesthetic and reconstructive surgery. Major trends in the forecast period include regulatory frameworks, advanced biomaterials, cell-based approaches, enhanced vascularization technique, and advanced bio fabrication methods.
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How has the bioengineered skin substitutes market evolved, and what factors have shaped its growth?
The rising number of burn cases is expected to propel the growth of the bioengineered skin substitute market going forward. Burn cases refer to injuries caused by skin or other organic tissue damage, primarily due to heat, radiation, electricity, friction, or chemicals. The burn cases are caused due to inadequate safety measures, irresponsible use of flammable materials, and lack of awareness about fire hazards and proper safety protocols. Bioengineered skin substitutes provide a temporary or permanent replacement for damaged skin, promoting healing, reducing the risk of infection, and improving functional and cosmetic outcomes. For instance, in November 2023, according to an analysis of inpatient care at burn centers published by the American Burn Association, a US-based nonprofit organization, there were 30,135 burn cases in the U.S. in 2022, contributing to a five-year total of 152,312 cases, with an estimated 1 in 10,000 people requiring inpatient hospitalization at a burn center annually. Therefore, the rising number of burn cases is driving the growth of the bioengineered skin substitute market.
What are the major segments of the bioengineered skin substitutes market?
The bioengineered skin substitutesmarket covered in this report is segmented –
1) By Product: Acellular, Allogeneic, Xenogeneic, Autologous, Other Products
2) By Application: Acute Wounds, Chronic Wounds
3) By End User: Wound Care Centers, Hospitals, Specialty Clinics, Other End Users
Subsegments:
1) By Acellular Skin Substitutes: Acellular Dermal Matrix, Acellular Epidermal Matrix
2) By Allogeneic Skin Substitutes: Allogeneic Dermal Grafts, Allogeneic Epidermal Grafts
3) By Xenogeneic Skin Substitutes: Porcine-Derived Skin Substitutes, Bovine-Derived Skin Substitutes
4) By Autologous Skin Substitutes: Autologous Skin Grafts, Cultured Autologous Skin Cells
5) By Other Products: Bi-layered Skin Substitutes, Bioactive Skin Substitutes, Synthetic Skin Substitutes
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Which companies dominate the bioengineered skin substitutes market?
Major companies operating in the bioengineered skin substitutes market are Stryker Corporation, DePuy Synthes, Smith & Nephew Plc, ConvaTec Group PLC, Mallinckrodt Pharmaceuticals plc, Integra LifeSciences Holdings Corporation, Gunze Limited, Organogenesis Inc., LifeNet Health Inc., MiMedx Group Inc., Vericel Corporation, AlloSource Inc., Sientra Inc., PolyNovo Limited, Avita Medical Limited, Tissue Regenix Group, Amarantus Bioscience Holdings Inc., PolarityTE, Promethean LifeSciences Inc., Regenicin Inc.
How will evolving trends contribute to the growth of the bioengineered skin substitutes market?
Major companies operating in the bioengineered skin substitute market are developing fish skin grafts to enhance the effectiveness and versatility of skin substitutes. A fish-skin graft is a wound-healing material made from processed fish skin that helps support tissue regeneration and repair. For instance, in February 2024, Kerecis, an Iceland-based wound care company, launched Shield Standard, a bioengineered skin substitute that combines intact fish skin with a silicone backing. It is sourced from fish skin, serving as a natural scaffold for healing. Kerecis employs patented technology that uses minimal processing to retain the beneficial components of fish skin that enhance tissue regeneration. It offers unique features such as biocompatibility with human skin, natural moisture retention, and the ability to reduce the risk of infection, making it a promising option for treating various types of wounds, including chronic and acute injuries.
What are the key regional dynamics of the bioengineered skin substitutes market, and which region leads in market share?
North America was the largest region in the bioengineered skin substitutes market in 2024. The regions covered in the bioengineered skin substitutes market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Does The Bioengineered Skin Substitutes Market Report 2025 Offer?
The bioengineered skin substitutes market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
Bioengineered skin substitutes are artificial or lab-grown skin materials that are developed using biological, synthetic, or a combination of both materials to replicate the function and structure of human skin. These substitutes are primarily used for treating severe skin injuries or conditions that require skin replacement or regeneration, such as burns, chronic wounds, ulcers, or reconstructive surgeries.
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