At what pace is the cartilage degeneration market growing, and what is its estimated value?
The cartilage degeneration market size has grown strongly in recent years. It will grow from $12.63 billion in 2024 to $13.4 billion in 2025 at a compound annual growth rate (CAGR) of 6.2%. The growth in the historic period can be attributed to aging population, joint injuries, obesity epidemic, sports injuries, limited self-repair capacity.
The cartilage degeneration market size is expected to see strong growth in the next few years. It will grow to $16.62 billion in 2029 at a compound annual growth rate (CAGR) of 5.5%. The growth in the forecast period can be attributed to regenerative medicine advancements, biologic injections, tissue engineering solutions, precision medicine, robotics-assisted surgery. Major trends in the forecast period include stem cell therapies, 3D printing in orthopedics, gene therapy for cartilage repair, personalized rehabilitation programs, telemedicine for follow-up care.
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What are the top drivers to the rising demand in the cartilage degeneration market?
The increasing prevalence of obesity is expected to propel the growth of the cartilage degeneration market going forward. Obesity is a medical condition characterized by an excessive accumulation of body fat to the extent that it may harm a person’s health. Obesity can initiate and accelerate cartilage degeneration by increasing cartilage compressive forces and inflammatory cytokines. Obesity induces several pathological changes to the whole knee joint structure, including abnormal loading on the joint, joint malalignment, and muscle weakness. For instance, in May 2023, according to the Government Digital Service, a UK-based government body, in 2021–2022, around 63.8% of adults aged 18 years and over were overweight or living with obesity, an increase from 63.3% from the previous year. Further, among adults, 25.9% were estimated to be obese, which increased by 25.2% from 2020 to 2021. Therefore, the increasing prevalence of obesity is driving the growth of the cartilage degeneration market.
How is the cartilage degeneration market segmented?
The cartilage degeneration market covered in this report is segmented –
1) By Procedure: Joint Replacements, Chondroplasty, Osteochondral Transplants, Microfracture, Meniscus Transplants, Cell-Based Cartilage Resurfacing, Autologous Chondrocyte Implantation, Other Procedures
2) By Application: Knee, Hip, Other Applications
3) By End User: Hospitals And Specialty Clinics, Ambulatory Surgical Centers, Academic And Research Institutes
Subsegments:
1) By Joint Replacements: Knee Replacement (Partial, Total), Hip Replacement (Partial, Total), Shoulder Replacement (Total, Reverse), Other Joints (Ankle, Elbow, Wrist)
2) By Chondroplasty: Radiofrequency Ablation Chondroplasty, Mechanical Chondroplasty, Thermal Chondroplasty, Arthroscopic Chondroplasty
3) By Osteochondral Transplants: Autografts (OATS), Allografts (Fresh Osteochondral Allografts), Synthetic Implants
4) By Microfracture: Traditional Microfracture, Augmented Microfracture (with scaffolds or matrix implants)
5) By Meniscus Transplants: Allograft Meniscus Transplantation (Cryopreserved, Fresh Frozen), Synthetic Meniscus Implants
6) By Cell-Based Cartilage Resurfacing: Autologous Cell-Based Therapy, Allogeneic Cell-Based Therapy, Stem Cell-Based Cartilage Repair
7) By Autologous Chondrocyte Implantation (ACI): First-Generation ACI, Second-Generation ACI, Third-Generation ACI (MACI)
8) By Other Procedures: Arthroscopic Debridement, Osteotomy, Cartilage Repair Using Synthetic Scaffolds, Injection-Based Therapies (Hyaluronic Acid, PRP, Stem Cell Injections)
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Who are the top competitors in the cartilage degeneration market?
Major companies operating in the cartilage degeneration market report are Johnson & Johnson Services Inc., MEDIPOST Co. Ltd., Medtronic PLC, Stryker Corporation, Zimmer Biomet Holdings Inc., Smith and Nephew PLC, B Braun Melsungen AG, Osiris Therapeutics Inc., Arthrex Inc., Conmed Corporation, Orthocell Ltd., Bioventus LLC, Aesculap Inc., Vericel Corporation, Anika Therapeutics Inc., Geistlich Pharma AG, MatTek Corporation, Breg Inc., Isto Biologics Inc., OrthoTrophix LLC, CellGenix GmbH, CartiHeal Inc., Cayenne Medical Inc., Collagen Solutions PLC, Regentis Biomaterials Ltd., Histogen Inc., BioTime Inc., CollPlant Holdings Ltd.
What significant trends should we anticipate in the cartilage degeneration market over the forecast period?
Major companies operating in the cartilage degeneration market are developing innovative products, such as Agili-C, to support bone remodeling and cartilage regeneration. Agili-C is a cell-free, off-the-shelf implant used to repair cartilage and osteochondral defects in traumatic and osteoarthritic joints. For instance, in July 2023, CartiHeal Ltd., an Israel-based medical device company, announced its first commercial implantation of Agili-C. The implant’s goal is to encourage the natural process of articular cartilage and subchondral bone regeneration rather than relying on cells or growth factors. The implant is made from natural calcium carbonate, aragonite, derived from coral exoskeletons. The implant stimulates chondrocytes from the surrounding cartilage to migrate into the scaffold, depositing an extracellular matrix. This approval adds value to the implant by reassuring patients and healthcare providers that it is a safe and effective treatment option.
Which regional trends are influencing the cartilage degeneration market, and which area dominates the industry?
North America was the largest region in the cartilage degeneration market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cartilage degeneration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
What Does The Cartilage Degeneration Market Report 2025 Offer?
The cartilage degeneration market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
Cartilage degeneration refers to the gradual deterioration or breakdown of cartilage tissue, a smooth, flexible connective tissue covering the ends of bones in joints. Cartilage is a cushion that allows for smooth joint movement by reducing bone friction. Cartilage degeneration leads to pain, stiffness, and decreased joint function.
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