The vascular endothelial growth factor (VEGF) inhibitor market size has grown strongly in recent years. It will grow from $43.44 billion in 2024 to $46.64 billion in 2025 at a compound annual growth rate (CAGR) of 7.4%. The growth in the historic period can be attributed to increase in cancer prevalence, strong economic growth in emerging markets, increase in pharmaceutical R&D expenditure, increased healthcare expenditure, government initiatives and rapid growth in elderly population.
The vascular endothelial growth factor (VEGF) inhibitor market size is expected to see strong growth in the next few years. It will grow to $59.48 billion in 2029 at a compound annual growth rate (CAGR) of 6.3%. The growth in the forecast period can be attributed to increasing prevalence of cancer, rising prevalence of age-related macular degeneration (AMD), rise in healthcare expenditure, high potential of emerging economies, high penetration of the biosimilar drugs and increasing geriatric population. Major trends in the forecast period include offering combination therapies to patients in order to combat advanced cancers and improve patient life, focusing on strategic collaborations to boost innovations and establish category leadership, investing extensively in R&D activities for the development of effective and innovative drugs, focusing on the production of biosimilars in order to cater to a wider market by making treatment more affordable and focusing on reducing dosages for wet age-related macular degeneration (AMD) in order to improve patient welfare.
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What key drivers have fueled the vascular endothelial growth factor (vegf) inhibitor market’s development over the years?
The growing prevalence of cancer and macular degeneration diseases is expected to drive the VEGF inhibitor market. For instance, in January 2023, according to a report published by the American Cancer Society, a US-based health organization, it is anticipated that there will be around 59,610 new instances of leukemia of all types and approximately 23,710 fatalities in 2023 resulting from leukemia of all types in the United States. Additionally, an estimated 20,380 new cases of acute myeloid leukemia (AML) and about 11,310 AML-related deaths are expected in the same year. Hence, the rising prevalence of cancer along with macular degeneration disease aids in the vascular endothelial growth factor (VEGF) inhibitor market growth over the forecast period.
What is the segmentation for the vascular endothelial growth factor (vegf) inhibitor market?
The vascular endothelial growth factor (VEGF) inhibitor market covered in this report is segmented –
1) By Drugs Type: Avastin, Tecentriq, Lucentis, Tagrisso, Cometriq, Eylea, Other Drug Types
2) By Route Of Administration: Oral, Intravenous, Intravitreal
3) By Application: Oncology, Ophthalmology, Other Applications
Subsegments:
1) By Avastin: Oncology Applications, Ophthalmology Applications
2) By Tecentriq: Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Bladder Cancer, Triple-Negative Breast Cancer
3) By Lucentis: Wet Age-Related Macular Degeneration (AMD), Diabetic Retinopathy, Retinal Vein Occlusion
4) By Tagrisso: First-Line Treatment, Second-Line Treatment
5) By Cometriq: Medullary Thyroid Cancer, Renal Cell Carcinoma
6) By Eylea: Wet Age-Related Macular Degeneration (AMD), Diabetic Macular Edema (DME), Retinal Vein Occlusion (RVO)
7) By Other Drug Types: Immuno-Oncology Drugs, Anti-Angiogenic Agents, Other Monoclonal Antibodies
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Who are the most influential companies in the vascular endothelial growth factor (vegf) inhibitor market?
Major companies operating in the vascular endothelial growth factor (VEGF) inhibitor market include F. Hoffmann-La Roche AG, Bayer AG, Regeneron Pharmaceuticals Inc., AstraZeneca Plc., Novartis AG, Pfizer Inc., Eli Lilly and Company, Exelixis Inc., Amgen Inc., Sanofi S.A., Cipla Limited, Biocon, Dr. Reddy’s Laboratories, Chi-Med, Innovent Biologics, Daiichi Sankyo, Chugai Pharmaceutical Co. Ltd, Boehringer Ingelheim International GmbH, GlaxoSmithKline plc, Ipsen, Oxurion, Pharmstandard Group, Zentiva, Coherus BioSciences Inc., AVEO pharmaceuticals, Eisai Co. Ltd.
What are the top industry trends projected to impact the vascular endothelial growth factor (vegf) inhibitor market?
Key players operating in the VEGF inhibitor industry are undergoing various collaborations and partnerships to expand their product portfolio by developing new products. Product portfolio expansion is the strategic approach that companies use to grow their businesses and increase their market share by satisfying consumer demand. The process of product development includes conceptualization, design, development, and marketing of newly created or newly rebranded goods or services. For instance, in April 2024, Santen Pharmaceutical Co. Ltd., a Japan-based pharmaceutical company, in a partnership with Bayer Yakuhin, a Japan-based pharmaceutical and life sciences company, launched the Ophthalmic VEGF Inhibitor Eylea 8mg Solution for Intravitreal Injection 114.3 mg/mL. These are standard treatments for conditions such as age-related macular degeneration (nAMD) and diabetic macular edema (DME), which can lead to blindness. Eylea 8mg, with a higher concentration than its predecessor, offers an extended dosing interval of up to 16 weeks, reducing the frequency of intravitreal injections while maintaining efficacy and safety. This advancement aims to lessen the treatment burden on patients and set a new standard of care. It is a strategic partnership aimed at expanding the reach and availability of this innovative ophthalmic treatment.
What are the major regional insights for the vascular endothelial growth factor (vegf) inhibitor market, and which region holds the top position?
The countries covered in the vascular endothelial growth factor (VEGF) inhibitor market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Italy, Canada, Spain
What Does The Vascular Endothelial Growth Factor (VEGF) Inhibitor Market Report 2025 Offer?
The vascular endothelial growth factor (vegf) inhibitor market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
A VEGF inhibitor is an inhibitor that prevents planned cell death by acting as an anti-apoptotic factor for hematopoietic cells. VEGF increases vascular permeability, which may make it easier for tumors to spread via the bloodstream and receive more oxygen and nutrients.
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