What is the current size and annual growth rate of the complicated urinary tract infection treatment market?
The complicated urinary tract infection treatment market size has grown strongly in recent years. It will grow from $8.87 billion in 2024 to $9.47 billion in 2025 at a compound annual growth rate (CAGR) of 6.8%. The growth in the historical period can be attributed to the increasing prevalence of urinary tract infections, rising cases of antibiotic resistance, growing geriatric population, increased hospitalization rates, and rising awareness about UTIs.
The complicated urinary tract infection treatment market size is expected to see strong growth in the next few years. It will grow to $12.13 billion in 2029 at a compound annual growth rate (CAGR) of 6.4%. The growth in the forecast period can be attributed to the growing prevalence of multidrug-resistant pathogens, increasing focus on precision medicine, rising healthcare expenditure, increased use of rapid diagnostic testing, government initiatives, and funding for research. Major trends in the forecast period advancements in diagnostic techniques, expanding healthcare access in emerging markets, development of novel antibiotics, technological advancements in diagnostic tools, and adoption of combination therapies.
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Which major factors have contributed to the expansion of the complicated urinary tract infection treatment market?
Rising incidence of chronic kidney diseases is expected to propel the growth of the complicated urinary tract infection treatment market going forward. Chronic kidney disease (CKD) is a long-term condition characterized by the gradual loss of kidney function over time. The rising incidence of chronic kidney disease (CKD) is primarily due to increasing rates of diabetes and hypertension, along with aging populations and lifestyle factors such as obesity and smoking. Complicated urinary tract infection treatment supports chronic kidney disease (CKD) patients by preventing severe infections, such as pyelonephritis, that can exacerbate kidney damage, worsen renal function, and accelerate the progression of chronic kidney disease, ultimately reducing the risk of further complications and hospitalizations. For instance, in December 2024, according to the Australian Institute of Health and Welfare, the Australia-based government agency, chronic kidney disease was responsible for approximately 21,800 deaths in Australia in 2022. Furthermore, in May 2024, according to the Kidney Care UK, a UK-based non-profit organization, every year, there are 40-45,000 premature deaths in the UK due to chronic kidney disease. Therefore, the rising incidence of chronic kidney diseases drives the complicated urinary tract infection treatment market.
How is the complicated urinary tract infection treatment market segmented?
The complicated urinary tract infection treatment market covered in this report is segmented –
1) By Drug Class: Penicillin And combinations, Quinolones, Cephalosporin, Azoles And Amphotericin B, Nitro furans
2) By Distribution Channel: Hospital Pharmacies, Gynecology And Urology Clinics, Drug stores
3) By Application: Urethritis, Cystitis, Pyelonephritis
Subsegments:
1) By Penicillin And Combinations: Aminopenicillins, Beta-Lactamase Inhibitor Combinations
2) By Quinolones: Fluoroquinolones, Non-Fluoroquinolones
3) By Cephalosporin: First-Generation Cephalosporins, Second-Generation Cephalosporins, Third-Generation Cephalosporins, Fourth-Generation Cephalosporins, Fifth-Generation Cephalosporins
4) By Azoles And Amphotericin B: Triazoles, Imidazoles, Polyene Antifungals
5) By Nitrofurans: Nitrofurantoin, Furazolidone
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Who are the top competitors in the complicated urinary tract infection treatment market?
Major companies operating in the complicated urinary tract infection treatment market are Pfizer Inc., Merck & Co. Inc., AbbVie Inc., AstraZeneca PLC, Fresenius Kabi AG, GlaxoSmithKline plc, bioMérieux SA, Shionogi & Co. Ltd., Cipla Limited, Santen Pharmaceutical Co. Ltd., Orchid Pharma Limited, Melinta Therapeutics Inc., Spero Therapeutics Inc., Nabriva Therapeutics AG, Venatorx Pharmaceuticals Inc., Recce Pharmaceuticals Ltd, MerLion Pharmaceuticals Pte. Ltd., Entasis Therapeutics Holdings Inc., Allecra Therapeutics GmbH, Allergan Inc.
Which key trends are expected to influence the complicated urinary tract infection treatment market in the coming years?
Major companies operating in the complicated urinary tract infection treatment market are focusing on combating antibiotic resistance through novel antibiotics to enhance treatment efficacy and address emerging multidrug-resistant pathogens. Anti-infective therapies for complicated urinary tract infection treatment involve the use of targeted antibiotics or antimicrobial agents to eliminate or control infections, particularly in severe cases, where kidney involvement is present. For instance, in February 2024, Allecra Therapeutics, a Germany-based biopharmaceutical company, announced U.S. Food and Drug Administration (FDA) approval of EXBLIFEP (cefepime/enmetazobactam) for treating complicated urinary tract infections (cUTIs) in adults. The company also secured a five-year marketing exclusivity extension under the GAIN Act, which incentivizes the development of new anti-infective therapies. The study demonstrated that 79.1% of patients treated with cefepime/enmetazobactam achieved a composite response (clinical cure and microbiological eradication) compared to 58.9% of those treated with piperacillin/tazobactam.
Which regional trends are influencing the complicated urinary tract infection treatment market, and which area dominates the industry?
North America was the largest region in the complicated urinary tract infection treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the complicated urinary tract infection treatment market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Does The Complicated Urinary Tract Infection Treatment Market Report 2025 Offer?
The complicated urinary tract infection treatment market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
Complicated urinary tract infection treatment refers to the medical management of a urinary tract infection (UTI) that occurs in individuals with underlying conditions that increase the risk of treatment failure. Complicated urinary tract infection treatment involves the use of targeted antibiotics and supportive therapies to address infections caused by resistant pathogens or underlying conditions that complicate recovery. It is used to manage severe urinary tract infection in patients with structural abnormalities, immunocompromised conditions, or catheter use, ensuring effective infection control and preventing complications.
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