gaucher’s disease market size, gaucher’s disease market share, gaucher’s disease market share analysis, gaucher’s disease market statistics, gaucher’s disease market outlook, gaucher’s disease market segmentation
How much is the gaucher’s disease market worth, and how is it expected to expand?
The gaucher’s disease market size has grown strongly in recent years. It will grow from $1.68 billion in 2024 to $1.78 billion in 2025 at a compound annual growth rate (CAGR) of 5.9%. The growth in the historic period can be attributed to enzyme replacement therapy (ert) development, increasing disease awareness, genetic research and diagnosis, patient advocacy initiatives, government incentives for rare diseases.
The gaucher’s disease market size is expected to see strong growth in the next few years. It will grow to $2.21 billion in 2029 at a compound annual growth rate (CAGR) of 5.6%. The growth in the forecast period can be attributed to next-generation therapies, global patient registry expansion, improvements in access to treatment, personalized medicine approaches, regulatory support for rare diseases. Major trends in the forecast period include technological innovations in treatment monitoring, international collaborations in research, oral therapeutics advancements, expanded newborn screening programs, global collaboration for patient access.
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What are the top drivers to the rising demand in the gaucher’s disease market?
The rising prevalence of genetic abnormalities is expected to propel the growth of the Gaucher’s disease market going forward. Genetic abnormalities are changes or mutations that occur in the DNA sequence of a person’s genes and may result in abnormal features, functions, or characteristics. The inheritance pattern of Gaucher’s disease is autosomal recessive, which means that an individual must inherit two copies of the mutated GBA gene, one from each parent, to develop the disease. People with Gaucher’s disease do not make enough of this enzyme, which leads to a buildup of fatty substances called lipids in certain organs such as the spleen and liver. For instance, in 2023 according to the Cystic Fibrosis Foundation, a US-based non-profit organization, the total population with Cystic Fibrosis without lung transplant in 2022 was 31,171 which increased to 31,752 in 2023. Therefore, the rising prevalence of genetic abnormalities is driving the growth of the Gaucher’s disease market.
How is the gaucher’s disease market segmented?
The gaucher’s disease market covered in this report is segmented –
1) By Type: Gaucher Disease Type 1, Gaucher Disease Type 2, Gaucher Disease Type 3, Other Types
2) By Diagnosis: Physical Exam, Blood Tests, Imaging Tests, Preconception Screening And Prenatal Testing, Other Diagnoses
3) By Therapy: Enzyme Replacement Therapy, Substrate Reduction Therapy
4) By Route Of Administration: Oral, Parenteral, Other Routes Of Administration
5) By End User: Hospitals, Specialty Clinics, Homecare, Other End Users
Subsegments:
1) By Gaucher Disease Type 1: Enzyme Replacement Therapy (ERT), Substrate Reduction Therapy (SRT)
2) By Gaucher Disease Type 2: Supportive Care, Experimental Therapies
3) By Gaucher Disease Type 3: Enzyme Replacement Therapy (ERT), Symptomatic Management
4) By Other Types: Rare Variants Of Gaucher Disease, Related Syndromes
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Who are the top competitors in the gaucher’s disease market?
Major companies operating in the gaucher’s disease market report are Pfizer Inc., Johnson & Johnson, Merck and Co. Inc., Novartis AG, Sanofi S.A., Abbott Laboratories, GlaxoSmithKline PLC, Takeda Pharmaceutical Company Limited, Moderna Inc., Teva Pharmaceutical Industries Ltd., Boehringer Ingelheim International GmbH, BioMarin Pharmaceutical Inc., CHIESI Farmaceutici SPA, IntraBio Inc., REGENXBIO Inc., JCR Pharmaceuticals Co. Ltd., Ultragenyx Pharmaceutical Inc., Amicus Therapeutics Inc., Pharming Group N.V., Idorsia Pharmaceuticals Ltd., Centogene N.V., Protalix BioTherapeutics, AVROBIO Inc., Resverlogix Corp., GenSight Biologics S.A., ISU Abxis Co. Ltd., SIRION BIOTECH GmbH, Greenovation Biotech GmbH, Orphazyme A/S
What significant trends should we anticipate in the gaucher’s disease market over the forecast period?
Major companies operating in the Gaucher’s disease market are developing innovative technologies such as NGS (next-generation sequencing) to better serve the patients. Next-generation sequencing (NGS), also known as high-throughput sequencing, is a revolutionary technology that allows rapid and cost-effective sequencing of DNA and RNA molecules. For instance, in February 2023, Eurofins Genomics LLC, a US-based biotechnology company, launched a whole plasmid sequencing service utilizing advanced Gen3 NGS (next-generation sequencing) technology. This revolutionary offering delivers rapid, same-day results with impressive single-base accuracy of up to 99%. By strategically combining the strengths of Sanger sequencing’s accuracy and quick turnaround time with the comprehensive analysis capabilities of NGS, the whole plasmid sequencing service bridges the gap between these two methods. This service accommodates long DNA constructs from 2.5 to 300 kb. With this new approach, Eurofins Genomics US empowers researchers with a cost-effective, time-efficient solution for long-read sequencing, offering a unique blend of accuracy and speed in the realm of genetic analysis.
Innovative AAV Gene Therapy Advances Treatment For Gaucher Disease Type 1
Major companies operating in the Gaucher disease market are focusing on developing innovative products such as AAV gene therapy to provide a transformative, one-time gene therapy for Gaucher disease Type 1. Adeno-associated virus (AAV) gene therapy is a treatment that uses AAV vectors to deliver therapeutic genes to cells to correct disease-causing mutations. For instance, in January 2022, Freeline Therapeutics Holdings plc, a UK-based biotechnology company, announced the US FDA approval for the FLT201 for Gaucher Disease Type 1. FLT201 utilizes an advanced AAVS3 capsid with a liver-specific promoter to deliver a novel glucocerebrosidase variant (GCasevar85). This FDA-cleared IND marks the first AAV-mediated gene therapy to enter clinical trials for Gaucher disease Type 1, highlighting its potential to offer a new therapeutic option for patients.
Which regional trends are influencing the gaucher’s disease market, and which area dominates the industry?
North America was the largest region in the Gaucher’s disease market in 2024. Europe is expected to be the fastest growing region in the forecast period. The regions covered in the gaucher’s disease market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
What Does The Gaucher’s Disease Market Report 2025 Offer?
The gaucher’s disease market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
Gaucher’s disease is a rare genetic disorder that interferes with the metabolism of a particular kind of fat called glucocerebroside. This disorder is caused by the formation of a fatty substance called glucocerebroside within certain cells, particularly in the spleen, liver, bone marrow, and sometimes in the brain.
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