How big is the head and neck squamous cell carcinoma market today, and what are its future growth expectations?
The head and neck squamous cell carcinoma market size has grown strongly in recent years. It will grow from $1.81 billion in 2024 to $1.98 billion in 2025 at a compound annual growth rate (CAGR) of 9.4%. The growth in the historic period can be attributed to raise awareness and screening, growth of combination therapies, healthcare infrastructure development, rise in healthcare spending, and rise incidence of head and neck squamous cell carcinoma.
The head and neck squamous cell carcinoma market size is expected to see strong growth in the next few years. It will grow to $2.81 billion in 2029 at a compound annual growth rate (CAGR) of 9.2%. The growth in the forecast period can be attributed to rising tobacco consumption, rising geriatric population, favorable government policies, increasing incidence of cancer, and increasing consumption of alcohol. Major trends in the forecast period include targeted therapy adoption, investment in research, integration of immunotherapy, technological advancements, and advancements in drug formulation.
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What have been the primary factors driving the head and neck squamous cell carcinoma market’s growth?
The increasing consumption of tobacco and alcohol is expected to propel the growth of the head and neck squamous cell carcinoma market going forward. The rising consumption of tobacco and alcohol is attributed to factors such as cultural influences, social norms, stress, peer pressure, marketing, and the availability of these substances. Alcohol and tobacco consumption increases the risk of head and neck squamous cell carcinoma (HNSCC) by causing chronic irritation and damage to the mucosal lining, promoting genetic mutations, and impairing immune response, which collectively facilitate carcinogenesis in the head and neck region. For instance, in September 2024, according to the Centers for Disease Control and Prevention, a US-based government agency Tobacco use continues to be the primary cause of preventable disease and death in the United States. In 2022, approximately 49.2 million adults, or 19.8% (nearly 1 in 5), reported using tobacco products. Furthermore, in June 2024, according to data published by Digital, a UK-based National Health Service government department, in 2022, 81% of adults reported consuming alcohol in the past 12 months. A greater percentage of men (84%) compared to women (78%) had drunk alcohol during that period. Therefore, the increasing consumption of tobacco and alcohol is driving the growth of the head and neck squamous cell carcinoma market.
What are the key segments within the head and neck squamous cell carcinoma market?
The head and neck squamous cell carcinoma market covered in this report is segmented –
1) By Type: Salivary Gland, Oral And Oropharyngeal, Nasal Cavity And Paranasal Sinuses, Nasopharyngeal, Laryngeal, Hypopharyngeal
2) By Drug Class: Epidermal Growth Factor Receptor (Egfr) Inhibitors, Immune Checkpoint Inhibitors, Other Drug Class
3) By Route Of Administration: Intravenous, Oral, Other Routes Of Administration
4) By Treatment: Radiation Therapy, Chemotherapy, Immunotherapy
5) By End-user: Hospitals, Specialty Clinics, Ambulatory Surgical Centers
Subsegments:
1) By Salivary Gland: Major Salivary Glands (Parotid, Submandibular), Minor Salivary Glands
2) By Oral And Oropharyngeal: Oral Cavity Cancer, Oropharyngeal Cancer (Tonsils, Base Of Tongue)
3) By Nasal Cavity And Paranasal Sinuses: Nasal Cavity Cancer, Paranasal Sinus Cancer
4) By Nasopharyngeal: Nasopharyngeal Carcinoma
5) By Laryngeal: Supraglottic Laryngeal Cancer, Glottic Laryngeal Cancer, Subglottic Laryngeal Cancer
6) By Hypopharyngeal: Hypopharyngeal Cancer
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Which key players are shaping the head and neck squamous cell carcinoma market?
Major companies operating in the head and neck squamous cell carcinoma market are Pfizer Inc., F. Hoffmann-La Roche Ltd, Merck & Co. Inc., Bayer AG, Sanofi SA, Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis AG, GSK plc, Eli Lilly and Company, Boehringer Ingelheim International GmbH, Rakuten Medical Inc., Exelixis Inc., Akeso Inc., Fortress Biotech Inc., Hookipa Pharma Inc., MacroGenics Inc., Theriva Biologics Inc., Turnstone Biologics Inc., Nykode Therapeutics AS, Immutep Limited, Tizona Therapeutics Inc., Checkpoint Therapeutics Inc., Zenith Epigenetics Ltd.
How will emerging trends drive the head and neck squamous cell carcinoma market throughout the forecast period?
Major companies operating in the head and neck squamous cell carcinoma are adopting strategic partnership approach to develop innovative combination therapies. Strategic partnerships for head and neck squamous cell carcinoma enable companies to combine resources and expertise, accelerating R&D and enhancing innovation. These collaborations foster faster commercialization by expanding market reach and accessing new patient populations. For instance, in October 2024, Exelixis Inc., a US-based biotech company, partnered with Merck & Co. Inc., a US-based pharmaceutical company, to advance cancer treatments. The collaboration aims to evaluate the combination of zanzalintinib with KEYTRUDA and WELIREG, targeting improved outcomes for patients with head and neck squamous cell carcinoma (HNSCC) and renal cell carcinoma (RCC).
How do regional factors impact the head and neck squamous cell carcinoma market, and which region is the largest contributor?
North America was the largest region in the head and neck squamous cell carcinoma market in 2024.Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the head and neck squamous cell carcinoma market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
What Does The Head And Neck Squamous Cell Carcinoma Market Report 2025 Offer?
The head and neck squamous cell carcinoma market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.
Head and neck squamous cell carcinoma (HNSCC) refers to a malignant tumor that develops in the squamous epithelium of the upper aerodigestive tract, encompassing areas such as the oral cavity, pharynx, and larynx. It is one of the most common forms of head and neck cancer, often linked to risk factors such as tobacco use, alcohol consumption, and infections such as human papillomavirus (HPV).
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