In-Vitro Transcription Templates Market Growth Outlook Through 2024-2033

In-vitro transcription templates are DNA sequences designed to serve as the blueprint for RNA synthesis in a controlled laboratory setting. These templates contain specific promoter regions recognized by RNA polymerase, facilitating the production of RNA molecules for various applications, including research, diagnostic development, and therapeutic production. They providie a precise and reliable source for RNA generation, along with molecular biology and genetic research.

Sizing and Forecast
The in-vitro transcription templates market size has grown exponentially in recent years. It will grow from $0.82 billion in 2023 to $1.01 billion in 2024 at a compound annual growth rate (CAGR) of 23.4%. The growth in the historic period can be attributed to rise in cases of chronic diseases, increase in investments in R&D in healthcare and pharmaceutical sectors, improvements in gene therapy technology, collaborations and partnerships and developments in gene therapy.

The in-vitro transcription templates market size is expected to see exponential growth in the next few years. It will grow to $2.35 billion in 2028 at a compound annual growth rate (CAGR) of 23.5%. The growth in the forecast period can be attributed to Increase in advancement in biotechnology, rise in focus in R&D activities, rise in usage of in-vitro transcription templates, demand for early diagnosis of diseases and increasing need for mRNA-based vaccines. Major trends in the forecast period include developments in RNA synthesis technologies, technological advancements, advancement in biotechnology, advancements in enzymatic synthesis techniques, and integration of automation and digitalization.

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Segmentation & Regional Insights
The in-vitro transcription templates market covered in this report is segmented –
1) By Treatment: Vaccine, Therapeutic
2) By Research Stage:  Exploratory, Clinical
3) By Disease: Cancer, Infectious Disease, Lifestyle Disease, Genetic Disease, Other Diseases
4) By End User: Pharmaceutical And Biotechnology Companies, Contract Research Organizations (CROs) And Contract Manufacturing Organizations (CMOs), Academics And Research, Other End Users

North America was the largest region in the in-vitro transcription templates market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the in-vitro transcription templates market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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Major Driver Impacting Market Growth
The increasing focus on gene therapy is expected to propel the growth of the in-vitro transcription templates market. Gene therapy involves modifying genes within cells to treat or prevent diseases by correcting defective genes. Advances in technologies such as CRISPR, significant investment, and recent treatment successes have increased focus on this approach. In-vitro transcription templates help in gene therapy by providing the RNA molecules necessary for mRNA-based therapies, siRNA-based therapies, and gene editing technologies, enabling the treatment of genetic disorders and diseases. For instance, in March 2024, the Food and Drug Administration (FDA), a US-based federal agency of the Department of Health and Human Services, estimated that 36 gene therapies were approved by the FDA, with an additional 500 in the pipeline and the expectation that 10-20 will be approved annually by 2025. Therefore, the increasing focus on gene therapy is driving the growth of the in-vitro transcription templates market.

Key Industry Players
Major companies operating in the in-vitro transcription templates market are Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Eurofins Genomics LLC, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., Qiagen N.V., Integrated DNA Technologies Inc., Promega Corporation, Genescript Biotech Corporation, Takara Bio Inc., New England Biolabs, OriGene Technologies Inc., Cayman Chemical, Synthego Corporation, Synbio Technologies, Creative Diagnostics, VectorBuilder Inc., Bio-Synthesis Inc., TriLink BioTechnologies, Norgen Biotek Corporation, Genaxxon BioScience GmbH, Enzo Life Sciences Inc., GeneCopoeia

The in-vitro transcription templates market report table of contents includes:
1. Executive Summary
2. Market Characteristics
3. Market Trends And Strategies
4. Impact Of COVID-19
5. Market Size And Growth
6. Segmentation
7. Regional And Country Analysis
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27. Competitive Landscape And Company Profiles
28. Key Mergers And Acquisitions
29. Future Outlook and Potential Analysis

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