Large and small-scale bioprocessing are essential components of the biotechnology and pharmaceutical industries that involve using living cells or their components to obtain desired products, such as pharmaceuticals, chemicals, and biofuels. Large-scale bioprocessing refers to the industrial-level production of biological products involving large bioreactors and extensive infrastructure. In contrast, Small-scale bioprocessing consists of the production of biological products on a smaller scale, often for research, development, pilot studies, or niche markets.
Sizing and Forecast
The large and small-scale bioprocessing market size has grown rapidly in recent years. It will grow from $52.59 billion in 2023 to $59.63 billion in 2024 at a compound annual growth rate (CAGR) of 13.4%. The growth in the historic period can be attributed to medical industry growth, regulatory standards, technological advancements, pharmaceutical and biotechnology growth, and food safety concerns.
The large and small-scale bioprocessing market size is expected to see rapid growth in the next few years. It will grow to $99.03 billion in 2028 at a compound annual growth rate (CAGR) of 13.5%. The growth in the forecast period can be attributed to increasing healthcare expenditure, the expansion of pharmaceutical and biotechnology sectors, technological innovations, regulatory pressures, rising awareness of food safety, and the aftermath of the COVID-19 pandemic. Major trends in the forecast period include the adoption of advanced technologies, geographical expansion, outsourcing of sterilization services, sustainable practices, hybrid sterilization techniques, and customized sterilization solutions.
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Segmentation & Regional Insights
The large and small-scale bioprocessing market covered in this report is segmented –
1) By Product: Bioreactors Or Fermenters, Cell Culture Products, Filtration Assemblies, Bioreactors Accessories, Bags And Containers, Other Products
2) By Mode: In-house, Outsourced
3) By Workflow: Downstream Processing, Fermentation, Upstream Processing
4) By Scale: Industrial Scale, Small Scale
5) By Application: Biopharmaceuticals, Specialty Industrial Chemicals, Environmental Aids
North America was the largest region in the large and small-scale bioprocessing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the large and small-scale bioprocessing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
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Major Driver Impacting Market Growth
The growing demand for biologics is expected to propel the growth of the large and small-scale bioprocessing market going forward. Biologics refer to medicinal products derived from living organisms or their components, including vaccines, blood and blood components, gene therapies, tissues, and recombinant therapeutic proteins. The growing demand for biologics is due to advancements in biotechnology, increased understanding of disease mechanisms, and the demand for targeted and personalized therapies. Both large-scale and small-scale bioprocessing are integral to biologics’ successful development and commercialization. Small-scale bioprocessing is essential for early-stage development, optimization, and feasibility studies. In contrast, large-scale bioprocessing ensures that biologics are produced efficiently, consistently, and in compliance with regulatory standards for commercial distribution. For instance, in February 2024, according to the National Library of Medicine, a US-based medical library, in 2023, the Food and Drug Administration (FDA) approved 55 new drugs, including 29 new chemical entities (NCEs) and 25 new biological entities (NBEs), marking a 50% increase compared to the 37 approvals in 2022. Therefore, the growing demand for biologics drives the growth of the large and small-scale bioprocessing market.
Key Industry Players
Major companies operating in the large and small-scale bioprocessing market are F. Hoffmann-La Roche AG, Merck & Co. Inc., Bayer AG, Sanofi S.A., Bristol Myers Squibb Company, Thermo Fisher Scientific Inc., AstraZeneca PLC, Novartis AG, GlaxoSmithKline PLC, 3M Company, Takeda Pharmaceutical Company Ltd., Danaher Corporation, Boehringer Ingelheim International GmbH, Novo Nordisk A/S, Becton Dickinson and Company (BD), Teva Pharmaceutical Industries Ltd., DAIICHI SANKYO COMPANY LIMITED, Lonza Group, Sun Pharmaceutical Industries Ltd., GE Healthcare Life Sciences, Sartorius AG, Dr. Reddy’s Laboratories Ltd., Alkem Laboratories Limited, Piramal Enterprises Ltd
The large and small-scale bioprocessing market report table of contents includes:
1. Executive Summary
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32. Global Large And Small-Scale Bioprocessing Market Competitive Benchmarking
36. Appendix
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