Categories: Healthcare

Ligases Enzyme Market Forecast 2024-2033: Growth Rate, Drivers, And Trends

The Ligases Enzyme Global Market Report 2024 by The Business Research Company provides market overview across 60+ geographies in the seven regions – Asia-Pacific, Western Europe, Eastern Europe, North America, South America, the Middle East, and Africa, encompassing 27 major global industries. The report presents a comprehensive analysis over a ten-year historic period (2010-2021) and extends its insights into a ten-year forecast period (2023-2033).

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According to The Business Research Company’s Ligases Enzyme Global Market Report 2024, The ligases enzyme market size has grown rapidly in recent years. It will grow from $2.89 billion in 2023 to $3.21 billion in 2024 at a compound annual growth rate (CAGR) of 11.3%. The growth in the historic period can be attributed to initial discovery and development of ligase enzymes, growth of the biotechnology industry, increased understanding of dna repair mechanisms, expansion of genetic engineering applications, rise in demand for molecular diagnostics.

The ligases enzyme market size is expected to see rapid growth in the next few years. It will grow to $4.92 billion in 2028 at a compound annual growth rate (CAGR) of 11.2%. The growth in the forecast period can be attributed to expansion of personalized medicine applications, growing focus on synthetic biology, adoption of ligase enzymes in drug development, increased demand for molecular diagnostics, integration of ligases in next-generation sequencing. Major trends in the forecast period include development of engineered ligases for specific applications, integration of ligase enzymes in crispr-based technologies, customization of ligase-based assays for research and diagnostics, rise of ligase-based isothermal amplification methods, adoption of ligase chain reaction (lcr) in diagnostic assays.

The increasing prevalence of cancer and genetic disorders is expected to propel the growth of the ligase’s enzyme market going forward. Cancer refers to a group of diseases characterized by the uncontrolled growth and spread of abnormal cells, and genetic disorders refer to a wide range of medical conditions caused by abnormalities or mutations in an individual’s genetic material, particularly in their DNA. Ligases enzymes are essential for DNA replication, repair, and recombination. In cancer, ligases can be used to repair damaged DNA, leading to the uncontrolled growth of cells. Ligases can also be used to target and kill cells with genetic disorders. For instance, in June 2023, according to the reports shared by the Centers for Disease Control and Prevention, a US-based government agency, in the United States, 1,603,844 new instances of cancer were reported in 2020, and 602,347 cancer-related deaths were recorded. Furthermore, 403 new cancer cases and 144 cancer-related deaths were reported for every 100,000 people. Furthermore, in February 2023, according to Gene People UK, a UK-based registered charity group, around 1 in 25 children are affected by a genetic condition in the UK, leading to more than 2.4 million children and adults in the UK living with a genetic disorder, and 30,000 babies and children are newly diagnosed each year. Therefore, the increasing prevalence of cancer and genetic disorders is driving the growth of the ligase’s enzyme market.

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The ligases enzyme market covered in this report is segmented –

1) By Type: E. coli DNA ligase, T4 DNA Ligase, Mammalian Ligases, Thermostable Ligases

2) By Source: Microorganisms, Animal, Plant

3) By Application: Ligase Chain Reaction (LCR), Ligase Detection Reaction (LDR), Next-Generation Sequencing (NGS), Repeat Expansion Detection (RED), Rolling Circle Amplification (RCA), Proximity Ligation Assay (PLA), Molecular Cloning, Ligation Mediated PCR, Mutation Detection

4) By End-User: Research Laboratories And Institutions, Pharmaceutical And Biopharmaceutical Companies, Diagnostic Laboratories

Product innovation is a key trend gaining popularity in the ligase’s enzyme market. Major companies operating in the ligase’s enzyme market are developing innovative ligases enzymes to sustain their position in the market. For instance, in December 2021, ArcticZymes Technologies ASA, a Norway-based biotechnology company, launched ArcticZymes R2D Ligase, an innovative patent-pending ligase with novel specificity enabling the ligation of DNA to both ends of RNA using a DNA splint. The enzyme is projected to be widely applicable in molecular diagnostics, next-generation sequencing, and gene and RNA synthesis applications for possible therapeutic applications. Additionally, it has a unique substrate specificity that allows it to ligate DNA to both the 5′- and the 3′-ends of RNA in the presence of a DNA template, positioning the lightable ends of DNA and RNA. It is highly active and efficient, making it ideal for various applications.

The ligases enzyme market report table of contents includes: