The Business Research Company’s report on the Ligases Enzyme Market provides insights into the global market size, growth rate, regional distribution, competitive landscape, key segments, emerging trends, and strategic opportunities.
How have key drivers contributed to the rapid growth of the ligases enzyme market?
The increasing prevalence of cancer and genetic disorders is expected to propel the growth of the ligase’s enzyme market going forward. Cancer refers to a group of diseases characterized by the uncontrolled growth and spread of abnormal cells, and genetic disorders refer to a wide range of medical conditions caused by abnormalities or mutations in an individual’s genetic material, particularly in their DNA. Ligases enzymes are essential for DNA replication, repair, and recombination. In cancer, ligases can be used to repair damaged DNA, leading to the uncontrolled growth of cells. Ligases can also be used to target and kill cells with genetic disorders. For instance, in July 2024, according to the Australian Institute of Health and Welfare, an Australia-based government agency, in Australia the number of cancer cases diagnosed increased from 160,570 in 2022 to 164,694 in 2023, reflecting a notable rise over the year. This upward trend highlights the growing prevalence of cancer within the country. Furthermore, 403 new cancer cases and 144 cancer-related deaths were reported for every 100,000 people. Furthermore, in February 2023, according to Gene People UK, a UK-based registered charity group, around 1 in 25 children are affected by a genetic condition in the UK, leading to more than 2.4 million children and adults in the UK living with a genetic disorder, and 30,000 babies and children are newly diagnosed each year. Therefore, the increasing prevalence of cancer and genetic disorders is driving the growth of the ligase’s enzyme market.
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How has the ligases enzyme market size evolved, and what are the latest forecasts for its expansion?
The ligases enzyme market size has grown rapidly in recent years. It will grow from $3.23 billion in 2024 to $3.58 billion in 2025 at a compound annual growth rate (CAGR) of 10.8%. The growth in the historic period can be attributed to the initial discovery and development of ligase enzymes, growth of the biotechnology industry, increased understanding of DNA repair mechanisms, expansion of genetic engineering applications, and rise in demand for molecular diagnostics
The ligases enzyme market size is expected to see rapid growth in the next few years. It will grow to $5.64 billion in 2029 at a compound annual growth rate (CAGR) of 12.0%. The growth in the forecast period can be attributed to the expansion of personalized medicine applications, growing focus on synthetic biology, adoption of ligase enzymes in drug development, increased demand for molecular diagnostics, and integration of ligases in next-generation sequencing. Major trends in the forecast period include the development of engineered ligases for specific applications, integration of ligase enzymes in CRISPR-based technologies, customization of ligase-based assays for research and diagnostics, rise of ligase-based isothermal amplification methods, adoption of ligase chain reaction (LCR) in diagnostic assays.
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Which major companies dominate the ligases enzyme market?
Major companies operating in the ligases enzyme market include BASF SE, F. Hoffmann-La Roche AG, Thermo Fisher Scientific Inc., Merck KGaA, Agilent Technologies Inc., Illumina Inc., QIAGEN N.V., GenScript, Promega Corporation, Oxford Nanopore Technologies Limited, Takara Bio Inc., New England Biolabs Inc., BioVision Inc., Enzo Life Sciences, Zymo Research, LGC Biosearch Technologies, Genetix Biotech Asia Pvt. Ltd., BLIRT S.A., Jena Bioscience, Bioline, Creative Enzymes, ArcticZymes Technologies ASA
What trends will shape the future of the less lethal ammunition market?
Major companies operating in the ligases enzyme market are developing technologies such as nanopore technologies to enhance the precision and efficiency of DNA sequencing and manipulation, ultimately improving applications in genomics, synthetic biology, and personalized medicine. Nanopore technologies involve the use of nanopores to detect and analyze molecules, such as DNA or proteins, by measuring changes in ionic current as they pass through the pore. For instance, in February 2023, Eurofins Genomics, a US-based biotechnology company, launched the Express Oxford Nanopore Sequencing service. The service utilizes Oxford Nanopore technology, which allows for the sequencing of long DNA fragments. This is particularly beneficial for applications requiring comprehensive genomic analysis, such as metagenomics and structural variant detection.
Which region dominates the ligases enzyme market, and what factors contribute to its leadership?
North America was the largest region in the ligases enzyme market in 2024. Asia-Pacific is expected to be the fastest-growing region in the ligases enzyme market report during the forecast period. The regions covered in the ligases enzyme market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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How is the ligases enzyme market segmented, and which segment holds the largest share?
The ligases enzyme market covered in this report is segmented –
1) By Type: E. coli DNA ligase, T4 DNA Ligase, Mammalian Ligases, Thermostable Ligases
2) By Source: Microorganisms, Animal, Plant
3) By Application: Ligase Chain Reaction (LCR), Ligase Detection Reaction (LDR), Next-Generation Sequencing (NGS), Repeat Expansion Detection (RED), Rolling Circle Amplification (RCA), Proximity Ligation Assay (PLA), Molecular Cloning, Ligation Mediated PCR, Mutation Detection
4) By End-User: Research Laboratories And Institutions, Pharmaceutical And Biopharmaceutical Companies, Diagnostic Laboratories
Subsegments:
1) By E. coli DNA Ligase: Ligase I, Ligase II
2) By T4 DNA Ligase: Wild-Type T4 Ligase, Modified T4 Ligase
3) By Mammalian Ligases: Ligase IV, Ligase I
4) By Thermostable Ligases: Taq DNA Ligase, Pyrococcus Furiosus Ligase
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How is the ligases enzyme market defined?
Ligase enzymes refer to a class of proteins that catalyze the joining of two DNA strands. These enzymes are extensively used in biotechnology and pharmaceuticals as they are essential in various cellular processes, including DNA replication and protein synthesis.
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