Overview and Scope
Oligonucleotide synthesis is the chemical linking of nucleotides, precisely forming the desired sequenced product. This process is helpful in modern laboratory practice as it offers quick and affordable access to oligonucleotides manufactured to order with the necessary sequence.
Sizing and Forecast
The oligonucleotide synthesis market size has grown rapidly in recent years. It will grow from $8.85 billion in 2023 to $10.27 billion in 2024 at a compound annual growth rate (CAGR) of 16.0%. The growth in the historic period can be attributed to growth in biomedical research advancements, therapeutic development, biotechnology innovations, genomic studies, increasing dna technologies.
The oligonucleotide synthesis market size is expected to see rapid growth in the next few years. It will grow to $18.67 billion in 2028 at a compound annual growth rate (CAGR) of 16.1%. The growth in the forecast period can be attributed to emerging diagnostic tools, rna interference (rnai) therapies, regenerative medicine, nanotechnology applications, advancements in gene editing. Major trends in the forecast period include targeted drug development, innovative delivery systems, automated synthesis, crispr-cas technology, next-generation sequencing (ngs).
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Segmentation & Regional Insights
The oligonucleotide synthesis market covered in this report is segmented –
1) By Type: Custom Oligos, Predesigned Oligos
2) By Product Type: Oligonucleotides, Reagents, Equipment, Services, Purification, Modification
3) By Application: Therapeutic Applications, Research Applications, Diagnostic Applications
Top 5 Major Players:
North America was the largest region in the oligonucleotide synthesis market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the oligonucleotide synthesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
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Major Driver Impacting Market Growth
The rising prevalence of chronic diseases is expected to propel the growth of the oligonucleotide synthesis market going forward. Chronic diseases refer to conditions that last one year or longer and require continuous medical attention, which may worsen over time. Oligonucleotides, via various mechanisms, act on gene expression that causes chronic diseases. They can target mRNA, pre-mRNA, or non-coding RNA to modulate splicing events, induce degradation, or interfere with protein translation. For instance, in January 2022, according to the International Diabetes Federation, a Belgium-based organization of national diabetes associations, the global diabetes prevalence in 20–79-year-olds was 536.6 million in 2021 and is expected to increase by 12.2% in 2045. Furthermore, in September 2022, according to the World Health Organization, a Switzerland-based specialized agency of the United Nations, there were 41 million deaths, which is 74% of those caused by non-communicable diseases (NCDs) or chronic diseases every year globally. There were 17.9 million deaths from cardiovascular diseases, 9.3 million deaths from cancer, 4.1 million deaths from chronic respiratory diseases, and 2.0 million deaths from diabetes. Therefore, the rising prevalence of chronic and rare diseases is driving the growth of the oligonucleotide synthesis market.
Key Industry Players
Major companies operating in the oligonucleotide synthesis market report are Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, GE HealthCare Technologies Inc., Eurofins Scientific SE, Agilent Technologies Inc., Nitto Denko Avecia Inc., Alnylam Pharmaceuticals Inc., Maravai Life Sciences, LGC Limited, Ionis Pharmaceuticals Inc., GenScript Inc., Ajinomoto Bio-Pharma Services, Sarepta Therapeutics Inc., Integrated DNA Technologies Inc., Twist Bioscience Corporation, Eurogentec SA, Kaneka Eurogentec S.A., Biocomma Limited, Bio-Synthesis Inc., TriLink BioTechnologies Incorporated, Generi Biotech s.r.o., ATDBio Ltd., BioAutomation Corporation, Biolegio B.V., Dharmacon Research Inc.
The oligonucleotide synthesis market report table of contents includes:
1. Executive Summary
2. Oligonucleotide Synthesis Market Characteristics
3. Oligonucleotide Synthesis Market Trends And Strategies
4. Oligonucleotide Synthesis Market – Macro Economic Scenario
5. Global Oligonucleotide Synthesis Market Size and Growth
….
32. Global Oligonucleotide Synthesis Market Competitive Benchmarking
33. Global Oligonucleotide Synthesis Market Competitive Dashboard
34. Key Mergers And Acquisitions In The Oligonucleotide Synthesis Market
35. Oligonucleotide Synthesis Market Future Outlook and Potential Analysis
36. Appendix
List Of Tables:
Table 1: Global Historic Market Growth, 2018-2023, $ Billion
Table 2: Global Forecast Market Growth, 2023-2028F, 2033F, $ Billion
Table 3: Global Oligonucleotide Synthesis Market, Segmentation By Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Table 4: Global Oligonucleotide Synthesis Market, Segmentation By Product Type, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Table 5: Global Oligonucleotide Synthesis Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
….
Table 74: Thermo Fisher Scientific Inc. Financial Performance
Table 75: Danaher Corporation Financial Performance
Table 76: Merck KGaA Financial Performance
Table 77: GE HealthCare Technologies Inc. Financial Performance
Table 78: Eurofins Scientific SE Financial Performance
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