Post Operative Pain Management Industry to Witness 6.1% Growth, Reaching $49.89 Billion by 2029

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How much is the post operative pain management market worth, and how is it expected to expand?

The postoperative pain management market size has grown strongly in recent years. It will grow from $37.03 billion in 2024 to $39.38 billion in 2025 at a compound annual growth rate (CAGR) of 6.4%. The growth in the historic period can be attributed to increased demand for pain management drugs, prevalence of chronic disease, rising number of cancer patients having surgery, increase in the number of traffic accidents and relative trauma injuries, and increase in surgical procedures.

The postoperative pain management market size is expected to see strong growth in the next few years. It will grow to $49.89 billion in 2029 at a compound annual growth rate (CAGR) of 6.1%. The growth in the forecast period can be attributed to increasingly adopting multimodal analgesic approaches, increasing demand for non-opioid-based analgesics, increased research and development, increasing focus toward palliative care, and a growing number of surgical procedures. Major trends in the forecast period include the development of innovative drugs, personalized treatment strategies, technological advancements, the integration of digital health technologies, advanced pain management solutions, and the integration of telemedicine.

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Which industry factors have accelerated the post operative pain management market’s expansion?

The increasing number of surgical procedures is expected to propel the growth of the postoperative pain management market going forward. Surgical procedures refer to medical operations performed by trained surgeons to diagnose, treat, or manage diseases, injuries, or conditions. The increase in surgical procedures is driven by an aging population, rising chronic diseases, advancements in medical technology, improved healthcare access, and growing demand for elective surgeries. Postoperative pain management enhances recovery, reduces complications, improves patient comfort, and supports better surgical outcomes by effectively controlling pain and enabling faster rehabilitation. For instance, in December 2023, according to the UK Health Security Agency, a UK-based government agency, coronary artery bypass graft surgeries increased in 2023 with 27,524 surgeries compared to previous years. Therefore, the growing number of surgical procedures is driving the growth of the postoperative pain management market.

What are the primary segments of the post operative pain management market?

The post operative pain management market covered in this report is segmented –

1) By Pain Type: Acute Pain, Moderate Pain, Severe Pain

2) By Drug Class: Opioids, Non-steroidal anti-inflammatory drugs (NSAIDs), Cyclooxygenase-2-selective inhibitors (COX-2 inhibitors), Other Drug Classes

3) By Route Of Administration: Injectable, Oral, Topical, Other Routes Of Administration

4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Other Distribution Channels

5) By Application: Cancer Pain, Arthritic Pain, Neuropathic Pain, Musculoskeletal Pain, Migraine

Subsegments:

1) By Acute Pain: Non-Opioid Analgesics, Opioid Analgesics, Local Anesthetics, Other Acute Pain Treatments

2) By Moderate Pain: NSAIDs, Acetaminophen, Weak Opioids, Combination Therapies, Other Moderate Pain Treatments

3) By Severe Pain: Strong Opioids, Patient-Controlled Analgesia (PCA), Epidural Analgesia, Nerve Blocks, Other Severe Pain Treatments

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Which firms are leading the post operative pain management market?

Major companies operating in the post operative pain management market are Johnson & Johnson, Merck & Co. Inc., Bayer AG, Novartis AG, Sun Pharmaceutical Industries Ltd., Cipla Inc., Hikma Pharmaceuticals PLC, Mallinckrodt plc, Pacira BioSciences Inc, Endo International plc, AFT Pharmaceuticals Limited, Heron Therapeutics Inc., Cara Therapeutics Inc., Teikoku Pharma USA Inc, Allay Therapeutics Inc, PainReform Ltd, Scilex Pharmaceuticals Inc., Taiwan Liposome Company Ltd, Concentric Analgesics Inc., Durect Corporation, Neumentum Inc., Trevena Inc., Virpax Pharmaceuticals Inc.

Which market trends are set to define the future of the post operative pain management market?

Major companies operating in the post-operative pain management market are focusing on developing technological advancements such as cryoablation probes to reduce pain effectively by targeting nerves with controlled cooling. A cryoablation probe is a medical device used to freeze and destroy targeted nerve tissues or abnormal cells, typically for pain management or treating tumors. For instance, in October 2024, AtriCure Inc., a US-based medical device company, launched the cryoSPHERE MAX. This probe improves postoperative pain management by temporarily blocking pain through targeted freezing of peripheral nerves. Its advanced design reduces freeze times and enhances tissue contact, ensuring more efficient and effective pain relief. This next-generation device includes enhancements in insulation, Nitrous Oxide gas usage, tactile tissue feedback, and real-time temperature monitoring.

Which geographic trends are shaping the post operative pain management market, and which region has the highest market share?

North America was the largest region in the postoperative pain management market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the post operative pain management market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Does The Post Operative Pain Management Market Report 2025 Offer?

The post operative pain management market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.

Postoperative pain management refers to the strategies and treatments used to relieve pain after a surgical procedure. It involves pharmacological and non-pharmacological approaches to enhance patient comfort, support recovery, reduce complications, and improve overall surgical outcomes.

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