What’s Driving the Prescription Orthopedic Drugs Market 2025-2034: Rising Prevalence Of Musculoskeletal Disorders Driving Demand For Treatment Solutions

How has the prescription orthopedic drugs market evolved, and where is it heading next?

The prescription orthopedic drugs market size has grown strongly in recent years. It will grow from $48.41 billion in 2024 to $51.55 billion in 2025 at a compound annual growth rate (CAGR) of 6.5%. The growth in the historic period can be attributed to the rise in the prevalence of musculoskeletal disorders, the increase in the geriatric population, the growth in awareness of osteoporosis treatments, the expanding healthcare access in developing regions, and the increase in sports-related injuries worldwide.

The prescription orthopedic drugs market size is expected to see strong growth in the next few years. It will grow to $65.32 billion in 2029 at a compound annual growth rate (CAGR) of 6.1%. The growth in the forecast period can be attributed to growing demand for biologics, increasing geriatric population, expanding healthcare access in emerging markets, rising prevalence of chronic musculoskeletal disorders, and increasing investments in orthopedic drug research and development. Major trends in the forecast period include advancements in targeted biologics, adoption of regenerative medicine therapies, personalized drug formulations, advancements in minimally invasive delivery methods, enhanced drug efficacy through gene therapy, innovations in injectable formulations, and innovations in artificial intelligence for drug development and clinical decision-making.

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What are the key drivers behind the rapid expansion of the prescription orthopedic drugs market?

The increasing incidence of musculoskeletal disorders is expected to drive the growth of the prescription orthopedic drugs market going forward. Musculoskeletal disorders (MSDs) are injuries and conditions that affect the movement and function of the human body’s musculoskeletal system, which includes muscles, tendons, ligaments, nerves, and joints, resulting in pain and reduced mobility. The increasing incidence of musculoskeletal disorders is primarily due to factors such as aging, occupational activities involving repetitive movements and awkward postures, lifestyle choices such as physical inactivity and poor nutrition, and genetic predispositions. Prescription orthopedic drugs play a vital role in managing musculoskeletal disorders by alleviating pain, reducing inflammation, and enhancing the healing process, thereby improving mobility and overall quality of life. For instance, in March 2023, according to the Office for Health Improvement and Disparities, a UK-based government department for public health, it was reported that, in 2022, 17.6% of people aged 16 and over reported having a long-term musculoskeletal (MSK) condition, such as arthritis or ongoing back or joint problems, up from 17.0% in 2021. Moreover, in July 2022, according to the World Health Organization, a Switzerland-based intergovernmental organization, around 1.71 billion people worldwide suffer from musculoskeletal disorders. Therefore, the increasing incidence of musculoskeletal disorders is driving the growth of the prescription orthopedic drugs market.

What is the segmentation for the prescription orthopedic drugs market?

The prescription orthopedic drugs market covered in this report is segmented –

1) By Drug Type: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), Opioids, Corticosteroids, Disease-Modifying Antirheumatic Drugs (DMARDs), Other Drug Types

2) By Application: Osteoarthritis, Rheumatoid Arthritis, Osteoporosis, Other Applications

3) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies

Subsegments:

1) By Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Ibuprofen, Naproxen, Diclofenac, Celecoxib, Indomethacin

2) By Opioids: Morphine, Oxycodone, Hydrocodone, Fentanyl, Tramadol

3) By Corticosteroids: Prednisone, Methylprednisolone, Dexamethasone, Hydrocortisone, Betamethasone

4) By Disease-Modifying Antirheumatic Drugs (DMARDs): Methotrexate, Hydroxychloroquine, Leflunomide, Sulfasalazine, Azathioprine

5) By Other Drug Types: Bisphosphonates, Calcitonin, Monoclonal Antibodies, Muscle Relaxants, Hyaluronic Acid Injections

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Who are the most influential companies in the prescription orthopedic drugs market?

Major companies operating in the prescription orthopedic drugs market are Pfizer Inc., Johnson & Johnson, Roche Holding AG, Merck KGaA, AbbVie Inc., Bayer AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca plc, GSK Plc, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Amgen Inc., Teva Pharmaceutical Industries Ltd., Mylan N.V., Biogen Inc., UCB S.A., Allergan plc, Penardo Biotech Pvt. Ltd., Horizon Therapeutics plc

What are the most influential trends expected to drive the prescription orthopedic drugs market forward?

Major companies operating in the prescription orthopedic drugs market are focusing on expanding indications for their drugs to broaden their market reach, enhance patient outcomes, and address unmet medical needs in various orthopedic conditions. For instance, in January 2023, Heron Therapeutics Inc., a US-based biotechnology company, received FDA approval for the expanded use of ZYNRELEF (bupivacaine and meloxicam) in soft tissue and orthopedic procedures, including foot and ankle surgeries. This extended-release solution is uniquely designed to provide prolonged pain relief for up to 72 hours, reducing or eliminating the need for opioids after surgery. The expanded indication now covers additional orthopedic and soft tissue procedures, including foot and ankle surgeries, broadening its applicability in clinical settings. Its innovative dual-drug combination delivers both local anesthetic and anti-inflammatory effects, making it a comprehensive option for managing post-operative pain with enhanced patient outcomes.

What are the major regional insights for the prescription orthopedic drugs market, and which region holds the top position?

North America was the largest region in the prescription orthopedic drugs market in 2024. The regions covered in the prescription orthopedic drugs market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Does The Prescription Orthopedic Drugs Market Report 2025 Offer?

The prescription orthopedic drugs market research report from The Business Research Company offers global market size, growth rate, regional shares, competitor analysis, detailed segments, trends, and opportunities.

Prescription orthopedic drugs refer to medications specifically prescribed to manage conditions affecting the musculoskeletal system, such as bones, joints, muscles, and ligaments. They are used for pain relief, inflammation reduction, and promoting healing in orthopedic injuries or disorders like arthritis, fractures, and tendonitis.

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