How the Protein Engineering Market Size and Growth Are Evolving: Key Insights for 2025

The Business Research Company’s report on the Protein Engineering Market provides insights into the global market size, growth rate, regional distribution, competitive landscape, key segments, emerging trends, and strategic opportunities.

Which emerging drivers are set to accelerate the growth of the protein engineering market further?

The increasing demand for protein-based drugs is driving the protein engineering market. Proteins that are used in drugs for therapeutic activity are protein-based drugs. The protein-based drugs or therapeutic proteins are medicines that are genetically engineered versions of naturally occurring human proteins. Protein engineering modifies protein sequences through the substitution, insertion, or deletion of nucleotides within the gene that encodes them in order to modify protein-based drugs that are better suited to particular applications. For instance, according to a study by Lancet Diabetes and Endocrinology journal, nearly 80 million people with type-2 diabetes will require insulin by 2030, a rise of 20%. Thus, increasing demand for protein-based drugs is driving the protein engineering market.

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What are the key factors influencing the forecasted market size of the protein engineering industry?

The protein engineering market size has grown rapidly in recent years. It will grow from $4.11 billion in 2024 to $4.69 billion in 2025 at a compound annual growth rate (CAGR) of 13.9%. The growth in the historic period can be attributed to scientific breakthroughs, early therapeutic success stories, biopharmaceutical revolution, rise of monoclonal antibodies, regulatory framework establishment.

The protein engineering market size is expected to see rapid growth in the next few years. It will grow to $8.33 billion in 2029 at a compound annual growth rate (CAGR) of 15.5%. The growth in the forecast period can be attributed to increasing demand for therapeutic proteins, advancements in biotechnology, drug development and research, rising prevalence of chronic diseases, focus on precision medicine. Major trends in the forecast period include advanced protein design tools, high-throughput screening techniques, artificial intelligence (ai) and machine learning, novel protein expression systems, CRISPR and gene editing technologies.

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Who are the leading competitors in the protein engineering market?

Major companies operating in the protein engineering market are Bruker Corporation, Codexis Inc., Danaher Corporation, Thermo Fisher Scientific Inc., GenScript Biotech Corporation, Agilent Technologies Inc., Bio-Rad Laboratories Inc., New England Biolabs Inc., PerkinElmer Inc., Amgen Inc., InvivoGen, Enantis s.r.o., Promega Corporation, Merck KGaA, Aragen Bioscience Inc., Creative BioMart, Waters Corporation, Genentech Inc., Novartis AG, Pfizer Inc., Roche Holding AG, Sanofi S.A., GlaxoSmithKline PLC, Johnson & Johnson, Eli Lilly and Company, AbbVie Inc., Bristol-Myers Squibb Company, AstraZeneca PLC, Biogen Inc., Abzena plc.

Which emerging trends are set to transform the protein engineering market landscape?

Major companies operating in protein engineering are focused to provide advance protein engineering foundry for better research and industrial applications. The foundry is full-stack protein engineering foundry that allows designers to test new proteins quickly and at scale, using multiple technologies. For instance, in April 2023, Adaptyv Bio, a Switzerland-based advanced nanotechnology and biotechnology company, launched protein engineering foundry. The foundry is an integrated lab that allows protein engineers to rapidly repeat their designs and create data on their proteins, lowering reagent use, time per experiment, and cost per data point generated by orders of magnitude when compared to current methods. The foundry is being developed to integrate with AI at every stage of the protein creation cycle, from sequence design to experimental protocol planning to protocol execution and recording of all data and metadata. The objective is to democratize protein design research and accelerate the field of protein engineering.

How do different geographies compare in terms of market share and growth potential in the protein engineering market?

North America was the largest region in the protein engineering market share in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the protein engineering market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

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Which major segments of the protein engineering market are experiencing the fastest growth?

The protein engineering market covered in this report is segmented –

1) By Product And Services: Instruments, Reagents, Services And Software

2) By Protein Type: Insulin, Monoclonal Antibodies, Coagulation Factors, Vaccines, Growth Factors, Other Protein Types

3) By Technology: Irrational Protein Design, Rational Protein Design

4) By End User: Pharmaceutical And Biotechnology Companies, Academic Research Institutes, Contract Research Organizations

Subsegments:

1) By Instruments: Protein Purification Systems, Spectroscopy And Imaging Systems, Mass Spectrometers

2) By Reagents: Enzymes, Antibodies, Labeling And Detection Reagents

3) By Services And Software: Custom Protein Engineering Services, Analytical Services, Consulting Services, Modeling And Simulation Software, Data Analysis Software, Bioinformatics Tools

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How is the protein engineering market defined, and what are its core characteristics?

Protein engineering is the process by which researchers can modify protein sequences through the substitution, insertion, or deletion of nucleotides within the gene that encodes them. This is done with the aim of obtaining modified proteins that are better suited to particular applications or purposes than unmodified proteins.

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