Upstream Bioprocessing Market Drivers, Trends And Market Analysis 2024-2033

Upstream Bioprocessing Market, 2024report by The Business Research Company offers comprehensive insights into the current state of the market and highlights future growth opportunities.
Market Size –
The upstream bioprocessing market size has grown rapidly in recent years. It will grow from $10.63 billion in 2023 to $12.03 billion in 2024 at a compound annual growth rate (CAGR) of 13.1%. The growth in the historic period can be attributed to rise in need for process optimization and contamination free, safe and efficient production of biomolecules, commercial success and rising demand for bio-therapeutics, rise in the implementation of process analytical technology, rise in chronic disease prevalence, and increased research into the production of biosimilar.
The upstream bioprocessing market size is expected to see rapid growth in the next few years. It will grow to $19.84 billion in 2028 at a compound annual growth rate (CAGR) of 13.3%. The growth in the forecast period can be attributed to commercial use of single-use bioreactors, outsourcing of biopharmaceutical manufacturing, rapid growth of pharmaceutical and biotechnology industries, rising adoption of single-use upstream bioprocessing, and increasing partnerships, mergers, acquisitions, and collaborations. Major trends in the forecast period include increasing investments in r&d in biopharmaceutical industry, technological advancements, advanced upstream bioprocessing technologies, development of new technologies and advanced filtration technologies.
Scope Of Upstream Bioprocessing MarketThe Business Research Company’s reports encompass a wide range of information, including:
1. Market Size (Historic and Forecast): Analysis of the market’s historical performance and projections for future growth.
2. Drivers: Examination of the key factors propelling market growth.
3. Trends: Identification of emerging trends and patterns shaping the market landscape.
4. Key Segments: Breakdown of the market into its primary segments and their respective performance.
5. Focus Regions and Geographies: Insight into the most critical regions and geographical areas influencing the market.
6. Macro Economic Factors: Assessment of broader economic elements impacting the market.
Upstream Bioprocessing Market Overview
Market Drivers –
The outsourcing of biopharmaceutical manufacturing is expected to propel the growth of the upstream bioprocessing market going forward. The outsourcing of biopharmaceutical manufacturing involves the delegation of certain stages of the production process to external entities, such as contract manufacturing organizations (CMOs) or contract development and manufacturing organizations (CDMOs). Outsourcing of biopharmaceutical manufacturing is driven by cost efficiency, focus on core competencies, flexibility in scaling production, access to specialized expertise, and risk mitigation. Outsourcing biopharmaceutical manufacturing in upstream bioprocessing market accelerates product development by leveraging external expertise, streamlining operations, and reducing costs. For instance, according to the BDO USA, a US member firm of BDO International, by 2025, contract development and manufacturing organizations and hybrid manufacturing companies will control 44% of the estimated 7,500kL of global mammalian capacity. Therefore, the outsourcing of biopharmaceutical manufacturing is driving the growth of the upstream bioprocessing market.
Market Trends –
Major companies operating in the upstream bioprocessing market are focused on developing advanced bioreactors to meet the needs of cell culture processes that enhance performance, flexibility, and scalability. Bioreactors are essential tools in upstream bioprocessing, enabling the efficient and controlled production of biopharmaceuticals through cell culture and biomolecule production. For instance, in April 2023, Cytiva, a US-based provider of life sciences products and solutions, introduced X-platform bioreactors designed to streamline single-use upstream bioprocessing procedures. The bioreactors consist of a tank, cabinet assembly, and human-machine interface (HMI). This modular design allows flexible arrangements without custom hardware or single-use bags. User-friendly features include an optimized vessel with a full-opening door, baffles, and improved cable management. Additionally, the online Bioreactor Scaler tool helps determine optimal parameters for successful scale-up.
The upstream bioprocessing market covered in this report is segmented –
1) By Product type: Bioreactors, Fermenters, Cell Culture Media, Filters, Bags And Containers
2) By Workflow: Media Preparation, Cell Culture, Cell Separation
3) By Usage type: Single-Use, Multi-Use
4) By Mode: In House, Outsourced
5) By End User: Contract Development and Manufacturing Organization (CDMOs) Or Contract Research Organization (CROs), Research And Academic Institutes, Biopharmaceutical Companies
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Regional Insights –
North America was the largest region in the upstream bioprocessing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the upstream bioprocessing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
Key Companies –
Major companies operating in the upstream bioprocessing market are Thermo Fisher Scientific Inc., Danaher Corp, Merck KGaA, GE HealthCare Technologies, Parker Hannifin Corp, Corning Inc., AGC Biologics, Avantor, AGC Inc., Boehringer Ingelheim International GmbH, Catalent Inc., Sartorius AG, Entegris Inc., Getinge AB, Bio-Rad Laboratories Inc., Samsung Biologics Co. Ltd., Eppendorf AG, Repligen Corporation, Takara Bio Inc., KBI Biopharma Inc., Rentschler Biopharma SE, Just Biotherapeutics Inc., PBS Biotech Inc., Stobbe Group, Applikon Biotechnology
Table of Contents
1. Executive Summary2. Upstream Bioprocessing Market Report Structure3. Upstream Bioprocessing Market Trends And Strategies4. Upstream Bioprocessing Market – Macro Economic Scenario5. Upstream Bioprocessing Market Size And Growth…..27. Upstream Bioprocessing Market Competitor Landscape And Company Profiles28. Key Mergers And Acquisitions
29. Future Outlook and Potential Analysis
30. Appendix
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